Comparison of Sequential Three-drug Regimens as Initial Therapy for Hiv-1 Infection. N Engl Similar Challenges with Retention in Care Issues
نویسندگان
چکیده
Michael P. Dubé, Robert A. Parker, Kathleen Mulligan, Pablo Tebas, Gregory K. Robbins, Ronenn Roubenoff, and Steven K. Grinspoon Division of Infectious Diseases, Indiana University, Indianapolis; Statistical and Data Analysis Center, Harvard School of Public Health, Divisions of Infectious Diseases and Nutrition, Harvard University, and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts; Division of Endocrinology, University of California at San Francisco, San Francisco; and Division of Infectious Diseases, University of Pennsylvania, Philadelphia
منابع مشابه
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
BACKGROUND It is unclear whether therapy for human immunodeficiency virus type 1 (HIV-1) should be initiated with a four-drug or two sequential three-drug regimens. METHODS In this multicenter trial we compared initial therapy involving four-drug regimens containing efavirenz and nelfinavir in combination with either didanosine and stavudine or zidovudine and lamivudine with therapy involving...
متن کاملComparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
BACKGROUND The optimal sequencing of antiretroviral regimens for the treatment of infection with human immunodeficiency virus type 1 (HIV-1) is unknown. We compared several different antiretroviral treatment strategies. METHODS This multicenter, randomized, partially double-blind trial used a factorial design to compare pairs of sequential three-drug regimens, starting with a regimen includin...
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تاریخ انتشار 2010